Innate immune reprogramming of chicken macrophages by sodium butyrate enhances reactive oxygen species–mediated antimicrobial responses in vitro

Innate immune reprogramming of chicken macrophages by sodium butyrate enhances reactive oxygen species–mediated antimicrobial responses in vitro

Innate immune reprogramming of chicken macrophages by sodium butyrate enhances reactive oxygen species–mediated antimicrobial responses in vitro AbstractIn the established model of classical trained immunity, metabolic and epigenetic hubs serve as central integrators of innate memory. While typically associated with proinflammatory reprogramming, the regulation of autophagy and cellular proteostasis remains essential for guiding macrophage diffe…