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How Phantom Limb Tricks Us

Brain scans of three participants show the primary motor cortex retains detailed limb maps up to five years post-amputation, offering new insights for phantom limb pain and neuroprosthetics.

Summary by Nautilus
Our brains play many tricks on us. Phantom limb, a condition where amputees feel vivid sensations in a limb that is no longer there, is one of the more mysterious. First documented in the 16th century by French military surgeon Ambroise Paré among soldiers who had lost limbs in battle, its name wasn’t coined until a few hundred years later by American Civil War surgeon and renowned neurologist Silas Weir Mitchell, who wrote a popular fictional a…

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In the brain, a lost limb is never really gone

Even years after an arm is amputated, the brain maintains a detailed map of the limb and tries to interact with this phantom appendage.

·Washington, United States
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An imaging study of amputated persons in the arms reveals that the brain map of the body remains remarkably stable even after years. This calls into question the long-standing idea that this brain map is completely reorganised after the loss of a limb to compensate for missing parts. This discovery could have important implications for the development of prosthetics and pain treatments for "phantom limbs." The primary somatosensorial cortex (S1)…

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Nautilus broke the news in on Tuesday, August 26, 2025.
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