Human Multi-Organ Chip Tracks Breast Cancer Spread to Bone and Lung

Multi-organ chip uncovers key mechanisms behind cancer metastasis

Cancer spreading beyond the primary tumor – a process known as metastasis – is responsible for at least two-thirds of cancer deaths.

Human multi-organ chip tracks breast cancer spread to bone and lung

Cancer spreading beyond the primary tumor—a process known as metastasis—is responsible for at least two-thirds of cancer deaths. Drugs targeting metastatic progression have largely failed, in part because of the lack of predictive models that would help identify the underlying mechanisms of metastasis.

'Metastasis-on-a-chip' to advance understanding of cancer spread

Cancer metastasis is responsible for at least two-thirds of cancer deaths. Researchers have developed a multi-organ chip that mimics how cancer cells spread to distant organs to gain new insights.

Human Multi-Organ Chip Offers New Insight Into Cancer Metastasis

Cancer metastasis is responsible for at least two-thirds of cancer deaths. Drugs targeting the metastatic progression have largely failed, in part due to the lack of predictive models that would help identify the underlying mechanisms of metastasis. Now, new work reports the development of a multi-organ chip that mimics how cancer cells spread from vascular flow to distant organs—the first model of cancer metastasis of its kind. The chip include…