HPV Vaccines Protect Against Cancer. Could They Benefit Pregnancy?
Researchers found 10% lower odds of preterm birth among women vaccinated before age 17, while results were weaker for later vaccination.
- A nationwide study published in the journal BMJ indicates that the quadrivalent HPV vaccine is associated with lower odds of various adverse pregnancy outcomes, especially when administered early in life.
- Researchers analyzed data from more than 624,000 births in Sweden, comparing women who received at least one dose of the HPV vaccine before conception to those who had not.
- Vaccinated women showed 10% lower odds of preterm birth and 11% lower odds of spontaneous preterm birth, while an Australian study also reported 3.2% lower rates of preterm birth among vaccinated cohorts.
- "Together with previous research showing the safety of human papillomavirus vaccination during pregnancy, our results suggest that human papillomavirus vaccination is not only safe with respect to pregnancy outcomes but may also confer additional benefits by reducing the risk of adverse events."
- Despite the findings, the study remains observational, meaning residual confounding may persist; researchers noted the data does not establish how many women would need to be vaccinated to prevent one adverse outcome.
14 Articles
14 Articles
Svenska Dagbladet
HPV vaccination appears to provide benefits beyond protection against cancer. Women who are vaccinated before pregnancy appear to have a lower risk of giving birth prematurely, among other things. “Protection is particularly good for those who are vaccinated before the age of 17,” says Jiayao Lei, one of the researchers behind a new study.
Study Finds Lower Pregnancy Risks in HPV-Vaccinated Women
(MedPage Today) -- Women vaccinated against human papillomavirus (HPV) were significantly less likely to have a range of adverse outcomes during pregnancy, according to a national case-control study from Sweden. Among nearly 625,000 births from...
Vaccines against papillomavirus, which provide protection against the development of cervical cancer, could also protect women from premature births.
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