Scientists Discover a Major Brain Change That Starts Around Age 50
4 Articles
4 Articles
Brain aging hides processes that begin long before the first memory failures appear. A new study has detected a transformation in the defenses of the hippocampus that could be related to cognitive deterioration and dementia.
Scientists Discover a Major Brain Change That Starts Around Age 50
NIH-supported findings reveal a previously unknown aspect of human brain aging that may contribute to cognitive decline and dementia risk later in life. Beginning in middle age, the immune cell population inside the hippocampus appears to undergo a major and rapid transformation. The hippocampus supports learning and memory, and the National Institutes of Health (NIH) [...]
A study by the National Institutes of Health (NIH) of the United States indicates that the panorama of the immune cells of the hippocampus, a brain region fundamental to learning and memory, undergoes a substantial and rapid remodeling from the middle age. This change, hitherto unknown, suggests a possible mechanism by which aging could contribute to chronic neuroinflammation that is commonly observed in neurodegenerative diseases, as summarized…
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