H Pylori Exposure ‘Linked’ to 22% of Bowel Cancer Cases Worldwide
Researchers found the microbe was linked to a 1.6-fold higher bowel cancer risk, with lower estimates in cohort-based studies.
- Published in eGastroenterology on Tuesday, a new exploratory study suggests exposure to the stomach microbe Helicobacter pylori may be associated with more than 1 in 5, or 22%, of bowel cancer cases worldwide.
- Gastroenterologist Iago Rodríguez-Lago emphasized that the research uses a mathematical model rather than clinical trials, meaning an association between the bacterium and cancer does not prove the infection causes these tumors.
- Data quality significantly impacts findings; when researchers restricted analysis to the strongest-quality studies, the estimated link dropped from 22% to about 1 in 9 cases, Colorectal Cancer Researcher at King's College London Dr Rosiered Brownson-Smith noted.
- Stratified by region, the Western Pacific and Mongolia showed the highest potential links at 25% and 36% respectively, while China recorded the highest absolute number of cases linked to exposure.
- Researchers cautioned that large-scale Helicobacter eradication raises antibiotic stewardship and resistance concerns, noting that observational data suggests benefits only emerge after more than 10 years of follow-up.
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24 Articles
A study by the University of California San Diego (United States), published in eGastroenterology magazine, suggests that exposure to the stomach microbe Helicobacter pylori could be associated with more than 1 in 5 cases of bowel cancer worldwide. According to the analysis, people born in recent decades could ... Continue reading "Helicobacter pylori: the silent enemy behind 20% of cases of bowel cancer"
H. Pylori Exposure and Colorectal Cancer: The Evidence Grows
(MedPage Today) -- Exposure to Helicobacter pylori, known for its role in gastric cancer, may also play a role in colorectal cancer (CRC), according to results from a risk-attribution modeling study. Based on estimates from 43 studies, H. pylori...
Common Stomach Bacteria Linked To 1 In 5 Bowel Cancer Cases In Global Analysis
An illustration of H pylori bacterium.Helicobacter pylori (H pylori), a common bacteria that can infect the stomach, has been linked to more than one in five bowel cancer cases worldwide, according to a new analysis. The bacteria has already been associated with stomach cancer in some individuals. Now, research suggests exposure might also be linked with up to a fifth of bowel cancer cases, too.And those born in more recent decades may be more a…
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