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Hayden Panettiere’s Death Highlights Risk of Overdose Death After Stopping and Resuming Drug Use

The coroner said she died from toxic effects of fentanyl and other drugs, and an autopsy found no signs of trauma.

  • On Tuesday, the Greenville County Coroner's Office officially ruled actress Hayden Panettiere's death accidental, determining she died from the toxic effects of fentanyl, 4-ANPP, alprazolam, methocarbamol, and quetiapine.
  • According to a Greenville City Police Department report, Panettiere was found unresponsive in a Greenville, South Carolina, apartment on August 16, with boyfriend Brian Hickerson and his brother present when she was declared dead.
  • Following Panettiere's recent release from a Malibu, California, treatment facility, police discovered a 'clear plastic bag of a white powdery substance' and pressed pills in her belongings, both testing positive for fentanyl.
  • Experts note that individuals who recently completed detoxification face significantly higher fatal overdose risks as tolerance levels drop, with studies showing risk five times higher immediately after ending treatment without medication.
  • Skip Panettiere, the actress' father, confirmed his daughter 'struggled with addiction since her early 20s' and suffered from postpartum depression, describing her relationship with Brian Hickerson as 'nothing but troubled.
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The coroner's report sheds light on the cause of Hayden Panettiere's sudden overdose death, bringing new tragic details to the fore. The 36-year-old actress passed away on August 16 at an Airbnb in Greenville, South Carolina. Her ex-boyfriend Brian Hickerson and his brother, Zach, were present at the event, who discovered her body. According to the Greenville County Medical Examiner's Office, her death was caused by the "toxic effects" of multip…

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Hayden Panettiere's death highlights risk of overdose death after stopping and resuming drug use

A coroner’s report notes that actor Hayden Panettiere had been in rehabilitation just weeks before she died from an accidental drug overdose

·New York, United States
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The actress died from the toxic effects of fentanyl and other substances, shortly before celebrating her 37th birthday.

·Marousi, Greece
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Libertatea.ro broke the news in Bucharest, Romania on Wednesday, September 23, 2026.
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