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Ris-Rez Improves Survival in Patients with Relapsed Small-Cell Lung Cancer

Summary by News Medical
Results from the randomized Phase III ARTEMIS-008 trial show that risvutatug rezetecan (Ris-Rez), a B7-H3-directed antibody-drug conjugate, significantly improved overall survival compared with topotecan in patients with relapsed small-cell lung cancer (SCLC) whose disease progressed on or after platinum-based chemotherapy.

4 Articles

Seoul – Immune checkpoint protein B7-H3 (CD276) enables a targeted attack with antibody-active conjugates in lung cancer. B7-H3 is expressed by cells of small cell bronchial carcinoma, but rarely by healthy cells. At the 2026 World Conference on Lung Cancer (WCLC) in Seoul, promising data on several lung cancers have been...

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Pharmaphorum broke the news on Monday, September 14, 2026.
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