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Blood Proteins Reveal MS Immune System Attack Starts Years Before Symptoms

UCSF researchers identified 21 blood proteins signaling early brain immune attacks, revealing MS begins seven years before symptoms and enabling potential early diagnosis.

Summary by Medical Xpress
By the time patients start seeking care for multiple sclerosis (MS), the disease has already been damaging their brains for years. But until recently, scientists didn't understand which brain cells were being targeted or when the injury began.

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A membrane that facilitates communication between neurons was detected seven years before the start of symptoms. Study creates new diagnostic opportunities and as far as possible prevention.

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Researchers at the University of California in San Francisco (UCSF, United States) have analyzed thousands of proteins present in the blood and, from that, have created the clearest image to date of how multiple sclerosis (MS) damages the brain of patients years before they experience symptoms and go to medical consultation.

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Medical Xpress broke the news in on Monday, October 20, 2025.
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