US EditionPaternal Microplastic Exposure Alters Metabolic Health in Offspring
Paternal microplastic exposure altered sperm RNA and caused sex-specific metabolic issues in offspring, with female mice showing diabetic traits under high-fat diet, researchers found.
- Recently, male mice exposed to microplastics before mating sired female offspring that failed insulin tolerance tests on a high-fat diet, the Journal of the Endocrine Society reports.
- Detection of microplastics in human tissues including testicular tissue and semen and widespread exposure through food, water and air motivated the study amid research literature focusing on direct exposure.
- Using PANDORA-seq, the team found microplastic exposure altered more than 4,000 small RNAs in sperm, and embryonic stem cell experiments with three candidate RNAs changed metabolic gene expression, matching female offspring liver inflammation.
- The researchers conclude the results indicate parental microplastic exposure may affect future offspring, and authors recommend men planning to have children reduce plastic exposure to protect offspring health.
- Key questions remain about human relevance and experimental causation as the study used a single polystyrene microplastics dose, examined only F1 offspring, had small sample sizes, and needs sperm RNA injection experiments.
11 Articles
11 Articles
Dad’s Microplastic Exposure May Prime Daughters For Insulin Resistance
Fathers exposed to microplastics before conception may be setting their daughters up for metabolic problems later in life. The post Dad’s Microplastic Exposure May Prime Daughters For Insulin Resistance appeared first on Study Finds.
Fathers’ microplastic exposure tied to their children’s metabolic problems
A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father’s exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring. The research, conducted using mouse models, highlights a previously unknown pathway through which environmental pollutants impact the health of future generations.
Paternal microplastic exposure alters metabolic health in offspring
A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father's exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring.
Fathers' microplastics exposure tied to their children's metabolic problems
A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father's exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring. The research, conducted using mouse models, highlights a previously unknown pathway through which environmental pollutants impact the health of future generations.
Father's Microplastic Exposure Linked to Diabetes in Daughters
A groundbreaking study has revealed a concerning link between a father’s exposure to microplastics and an increased risk of metabolic diseases, such as diabetes, in his female offspring. Conducted by researchers at the University of California, Riverside (UC Riverside), the study emphasizes how environmental pollutants can affect future generations through paternal lineage. Microplastics are tiny particles, measuring less than five millimeters, …
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