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AI Tool Estimates Biological Age From Photos to Predict Cancer Outcomes

Researchers found that faster facial aging over treatment was linked to lower survival, and the effect was strongest when photos were taken two years apart.

  • Scientists developed an AI tool called FaceAge that estimates cancer patient survival by analyzing changes in facial aging over time, with research published in Nature Communications revealing that accelerated facial aging is linked to lower survival probabilities.
  • By calculating the Face Aging Rate from serial photographs, researchers determined biological age changes relative to chronological age, allowing tracking of an individual's health status through routine clinical imagery.
  • Analyzing 2,279 patients at Mass General Brigham, researchers found that facial aging outpaced chronological aging by 40% on average, with Higher FAR significantly associated with decreased survival probability.
  • Raymond Mak of Mass General Brigham Cancer Institute said: "Deriving a Face Aging Rate from multiple, routine facial photographs allows for near real-time tracking of an individual's health," noting the tool may refine personalized treatment planning.
  • Study co-author Hugo Aerts added: "Tracking FaceAge over time from simple photos offers a non-invasive, cost-effective biomarker with potential to inform individuals of their health," as researchers hope to apply this tool to other chronic diseases.
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The Conway Daily SunThe Conway Daily Sun
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AI can predict which cancer patients will survive based on photos

It predicted patients with cancer who aged rapidly between photos taken over the course of their treatment had lower chances of survival.

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That someone has developed an application (called FaceAge) that promises to estimate the user's age from a 'selfi' may seem a mere curiosity. However, when something like this appears in a newspaper's Health section it is because there is something else. In this case, that its developers are also researchers at Mass General Brigham Hospital, and that the purpose of the 'app' goes far beyond vanity. The results of their latest study, published in…

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AI-Assessed Speed of Facial Aging Was Linked to Cancer Patient Survival Rate: U.S. Researchers Analyzed Photos of 2,279 Patients; Faster Facial Aging Becomes Lower Survival Rate. A study has found that facial photos kept in hospitals for treatment records can serve as clues to reading changes in cancer patients' health. The researchers...

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Medical Xpress broke the news on Tuesday, April 28, 2026.
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