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Everyday PFAS exposure alters placental function in early pregnancy

Summary by News Medical
This study measured real-life PFAS concentrations in first-trimester human placentas and used these data to create a pregnancy-relevant PFAS mixture. In 3D trophoblast spheroid models, the mixture altered invasion, hormone secretion, and gene expression without broadly reducing viability at environmentally relevant doses.

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They highlight the consequences of the exposure of pregnant women to eternal pollutants and phenols, present in food packaging or cosmetics.

·Paris, France
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The placenta regulates the exchange of nutrients, gases, and metabolic waste products between the pregnant woman and the fetus, thus ensuring healthy development. The first 90 days of pregnancy are particularly important, as the baby's organs develop during this sensitive period...

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News Medical broke the news in United States on Tuesday, December 9, 2025.
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