US EditionCRISPR Snips Away Extra Chromosomes, Offering New Hope for Down Syndrome Treatment
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A team of Japanese researchers have used multiple CRISPR-Cas9 tools to cut into fragments the additional chromosome that causes the disease, leading to its disappearance in certain cells
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CRISPR Snips Away Extra Chromosomes, Offering New Hope for Down Syndrome Treatment
Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers successfully removed extra copies of chromosome 21 in Down syndrome cell lines, restoring normal gene expression. This breakthrough suggests that, with further development, similar approaches could be applied to neurons and glial cells, offering a potential treatment [...]
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