Engineered dendritic cells boost cancer immunotherapy

Engineered dendritic cells boost cancer immunotherapy

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.

Engineered Dendritic Cells Harness Tumor EVs to Boost Cancer Immunotherapy

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s scouts—making them harder to detect and target. Dendritic cells normally collect tumor antigens and present them to T cells, which then attack cancer cells. Clinicians have tried to overcome tumor evasion by harvesting dendritic cells from patients, loa…

Engineering dendritic cells boosts cancer immunotherapy

18.12.2025 - Researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.