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Empty-handed neurons might cause neurodegenerative diseases

Summary by Eurek Alert
Tokyo, Japan – Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer’s. They used fruit flies to show that depletion of mitochondria in axons can directly lead to protein accumulation. At the same time, significantly high amounts of a protein called eIF2β were found. Restoring the levels to normal led to a recovery in protein recycling. Su…

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Sci Tech Daily broke the news in on Sunday, April 21, 2024.
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