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Eli Lilly Becomes First Trillion-Dollar Health Company

Driven by diabetes drug Mounjaro and obesity drug Zepbound, Eli Lilly's shares rose over 36% this year, with obesity and diabetes treatments now over half its revenue.

  • On Nov. 21, Eli Lilly reached a $1 trillion market valuation in trading Friday, briefly crossing the threshold before its stock pulled back in U.S. stock markets.
  • Lilly's surge follows sales of Mounjaro and Zepbound, which generated $11.54 billion and $4.93 billion by 2024, while shares rose more than 36% this year.
  • After winning approvals, Lilly now faces intensified competition as Pfizer paid $10 billion for Metsera earlier this month and two new injectable obesity drugs enter trials.
  • Some analysts predict the market could exceed $150 billion by the early 2030s, and Eli Lilly expects continued growth as insurance and approvals expand access with an oral version next year.
  • As a rare non-tech trillion-dollar firm, Eli Lilly is the first healthcare company to reach $1 trillion and only the second after Warren Buffett's Berkshire Hathaway, founded in 1876 with milestones like 1923's insulin and Prozac.
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Axios broke the news in Washington, United States on Sunday, November 23, 2025.
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