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FDA Authorizes Drug to Treat Cats and Kittens Infected with New World Screwworm

Credelio CAT, containing lotilaner, is now FDA-approved for treating New World screwworm in cats, addressing an emerging parasite threat near the U.S.-Mexico border.

  • The U.S. Food and Drug Administration issued an Emergency Use Authorization for Credelio CAT to treat New World screwworm in cats and kittens, Elanco said.
  • Since 2022, New World screwworm has progressed north, posing threats to livestock, while the FDA's earlier October EUA for dogs provided precedent for the feline authorization.
  • Laboratory and field studies on lotilaner, an isoxazoline, indicated 100% larvicidal effectiveness in two Malaysian cats and supported by studies in 11 naturally infested dogs in Brazil.
  • Available by prescription only, Credelio CAT requires licensed veterinarians to monitor for isoxazoline-associated neurologic risks, and the EUA limits its emergency use to the declaration's duration.
  • Elanco says the EUA equips veterinarians and cat owners with a ready-now treatment and reassurance if New World screwworm crosses into the U.S., addressing research comparing dog and cat veterinary visits .
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Johnson City PressJohnson City Press
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Elanco's Credelio™ CAT (lotilaner) Receives First FDA Emergency Use Authorization (EUA) for Treatment of New World Screwworm (NWS) in Cats

EUA to Treat Cats for NWS Issued Prior to Fly Being Detected in the U.S.; Action Prepares Veterinarians and Pet Owners with Treatment Options

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U.S. News broke the news in New York, United States on Friday, November 21, 2025.
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