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Doxycycline use in early pregnancy associated with higher risk of pregnancy loss

The study compared doxycycline with other antibiotics in women of reproductive age and found higher early pregnancy loss risk.

Summary by Medical Xpress
A retrospective, active-comparator cohort study found that doxycycline use for respiratory tract infections or acne during early pregnancy was associated with an increased risk for pregnancy loss. Given the frequent use of doxycycline by women of childbearing age, these findings underscore the importance of both clinicians and patients weighing the benefits and risks when considering treatment with doxycycline. The findings are published in Annals of Internal Medicine.

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Medical Xpress broke the news in Douglas, United Kingdom on Monday, November 9, 2026.
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