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Flu Cases Are Rising. Here’s What’s Driving the Surge and How to Protect Yourself

At least 49,000 hospitalizations have occurred, with experts warning mutations in the flu strain may reduce vaccine effectiveness amid rising holiday travel risks.

  • On Friday, the Centers for Disease Control and Prevention reported at least 4.6 million flu cases, 49,000 hospitalizations and 1,900 deaths in the United States this season.
  • Genetic surveillance shows nearly 90% of H3N2 viruses belong to subclade K , which differs genetically from this year’s flu vaccine and may evade some immunity.
  • Hospitals say Dr. Ari Cohen reports at least 1,900 deaths, including three children, with two pediatric deaths in the past week, and Massachusetts saw 1.9 percent of ER visits hospitalized as of Dec. 13.
  • Health officials recommend people 6 months and older get the flu vaccine, use four FDA-approved antiviral drugs within 1–2 days of symptoms, and clinicians advise staying home until fever-free for 24 hours.
  • At public-health laboratories, the DC Public Health Laboratory logs swabs from doctors' offices and hospitals and sends results to the CDC while officials warn holiday travelers could drive further spikes.
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News 4 San Antonio broke the news in San Antonio, United States on Sunday, December 21, 2025.
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