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3D Genome 'Entanglement' May Explain How Cephalopods Evolved Complex Brains

Researchers found ancient genome reshuffling created new DNA contacts that may have helped octopuses, squid and cuttlefish evolve complex nervous systems.

Summary by Phys.org
Octopuses, squid and cuttlefish, collectively known as coleoid cephalopods, have evolved exceptionally large and elaborately structured nervous systems capable of complex behaviors such as problem-solving and rapid camouflage. A new study by scientists at the University of Vienna suggests that the origins of this complexity may lie not just in the genes themselves, but in how the genome is organized in 3D.

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Kraken, Kalmare and Sepien have large and complex nervous systems. A new genome analysis now suggests that not only individual genes, but also the spatial folding of the DNA could have played a role for their evolution. Contacts between distant gene sequences could have changed the control of important genes and thus favored new developments. Vienna [...] The article DNA folding shows how cephalopods developed complex brains appeared first on sc…

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scinexx.de broke the news on Friday, October 9, 2026.
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