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Metformin Mimics Exercise-Related Metabolic Effects in Prostate Cancer Patients

The diabetes drug increased Lac-Phe levels in 7 patients, a signal researchers said may help counter hormone therapy-related metabolic syndrome.

Summary by News Medical
A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise's core biological effects in men with prostate cancer, raising levels of a molecule tied to energy balance and weight control even when patients are inactive.

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News for the Day and the Hour Latest News Today Metformin is a medicine used mainly to treat type 2 diabetes that helps control blood glucose levels. Scientists in the United States identified that the drug could be given another use as well. In men with prostate cancer, the drug could produce a similar effect to that generated by intense exercise in the body. It is because metformin raises the levels of a molecule key to energy balance and wei…

Metformin, a drug indicated for diabetes, could replicate the benefits of physical exercise in the treatment of prostate cancer, according to a study conducted by a team of researchers from Leonard M. Miller School of Medicine at the University of Miami.

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Medical Xpress broke the news in on Monday, April 6, 2026.
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