Single-Cell Spatial Atlas Profiles 850,000 Cells Across Breast Cancer Progression

Single-cell spatial atlas profiles 850,000 cells across breast cancer progression

Researchers at The University of Texas MD Anderson Cancer Center have created one of the most detailed maps to date of the cell environment surrounding ductal carcinoma in situ (DCIS), the most common form of preinvasive, or stage 0, breast cancer.

Cell changes around early breast cancers provide clues to why some cases become invasive

Researchers at The University of Texas MD Anderson Cancer Center have created one of the most detailed maps to date of the cell environment surrounding ductal carcinoma in situ (DCIS), the most common form of preinvasive, or stage 0, breast cancer. The findings may help explain why some lesions progress to invasive breast cancer and others do not, informing strategies to improve patient risk prediction and develop better targeted approaches for …

DCIS Cell Atlas Reveals Clues to Invasive Breast Cancer Progression

Researchers created a detailed map of the tumor microenvironment surrounding estrogen receptor-positive ductal carcinoma in situ, which may help better predict progression to invasive breast cancer and inform on future therapeutic strategies. The post DCIS Cell Atlas Reveals Clues to Invasive Breast Cancer Progression appeared first on GEN - Genetic Engineering and Biotechnology News.

Detailed Cellular Atlas Maps Microenvironment Changes in Preinvasive Stage

Researchers mapped over 850,000 cells to reveal microenvironment alterations and stromal structures surrounding preinvasive ductal carcinoma in situ breast lesions.