Combination Therapy Overcomes Treatment Resistance in Breast Cancer Models

Combination therapy overcomes treatment resistance in breast cancer models

A combination approach successfully overcame treatment resistance and led to durable responses in preclinical models of advanced breast cancer, according to researchers at The University of Texas MD Anderson Cancer Center. The targets at the center of this approach were identified by a new computational biology algorithm developed at UT MD Anderson called TargetScore, suggesting this tool could be used to develop new therapeutic strategies and a…

EZH2 Drives CDK4/6 Inhibitor Resistance in Metastatic Breast Cancer

Researchers have identified that cytosolic EZH2 functionally inactivates Rb to drive CDK4/6 inhibitor resistance in ER-positive, HER2-negative metastatic breast cancer, revealing an actionable therapeutic target.

New Study Shows Combination Therapy Beats Breast Cancer Resistance

Mega Doctor News Newswise – HOUSTON, Texas ― A combination approach successfully overcame treatment resistance and led to durable responses in preclinical models of advanced breast cancer, according to researchers at The University of Texas MD Anderson Cancer Center. The targets at the center of this approach were identified by a new computational biology algorithm developed at UT […]