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CRISPR-based epigenome and genome editing reveal novel roles for PLEC in cartilage biology, mechanobiology, and response to inflammation
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CRISPR-based epigenome and genome editing reveal novel roles for PLEC in cartilage biology, mechanobiology, and response to inflammation
Background Osteoarthritis (OA)-associated single nucleotide polymorphism (SNP) rs11780978 has previously been associated with differential methylation at sites within PLECgene and differential expression of PLEC in multiple joint tissues, including cartil...
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