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Scientists Use CRISPR to Create Allergy-Free Beagles

Researchers say the edited beagles showed no detectable Can f 1 protein and no skin-prick reaction in early tests, suggesting a new route for allergy-safe dogs.

  • On August 4, 2026, geneticist Matt Walker introduced Alfie and Bailey, two hypoallergenic beagles created by his company Kindred Companion Sciences using CRISPR to eliminate the Can f 1 allergen protein.
  • Walker, a lifelong dog allergy sufferer, founded Kindred Companion Sciences in 2020 to address allergies at their biological source, enabling pet ownership for people like himself.
  • Scientists used CRISPR-Cas9 to knock out the Can f 1 gene in dog skin cells, with Walker confirming success when skin-prick tests showed no allergic reaction to the dogs' saliva and fur.
  • Bioethicist Arthur Caplan of New York University warned the technology might discourage adoption of shelter animals, while critics cite risks of off-label use for selecting preferred traits.
  • Commercial availability remains years away as researchers must monitor long-term health effects and determine whether the method effectively soothes symptoms across a broader human population with dog allergies.
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Scientists from the US biotechnology company Kindred Companion Sciences presented two beagles, called Alfie and Bailey, which were genetically edited using the CRISPR-Cas9 technique to eliminate protein (Can f 1) that causes allergies.

·Guayaquil, Ecuador
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Discover Magazine broke the news in Wilmington, United States on Tuesday, August 4, 2026.
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