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Stimulant ADHD Medications Work Differently than Previously Thought

Research on 5,795 children shows ADHD stimulants activate brain reward and wakefulness centers, mimicking good sleep and masking sleep deprivation effects, study finds.

Summary by Medical Xpress
Prescription stimulants, such as Ritalin and Adderall, are widely used to treat attention deficit hyperactivity disorder (ADHD), including in children. In the U.S., about 3.5 million children aged 3 to 17 take an ADHD medication, a number that has increased as more children have been diagnosed with the neurodevelopmental disorder.

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JAMA Network broke the news on Wednesday, December 24, 2025.
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