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Blood Metabolites Reveal Who Will Develop Type 2 Diabetes Years Before Diagnosis

Summary by News Medical
This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites associated with long-term risk of type 2 diabetes in initially healthy adults. A validated 44-metabolite signature improved risk prediction beyond conventional factors, offering insights into biological pathways and opportunities for earlier, more precise prevention.

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Researchers identify dozens of metabolites and create a biological “signature” that predicts disease risk beyond traditional risk factorsResearchers from Mass General Brigham and Albert Einstein College of Medicine have identified that metabolites, small molecules in the blood that are created during metabolism, are associated with the risk of developing type 2 diabetes in the future. They have also discovered genetic and lifestyle factors that …

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Telegrafi broke the news in on Sunday, January 18, 2026.
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