Circulating levels of surfactant protein D (SP-D) and microfibril-associated glycoprotein 4 (MFAP4) exhibit limited associations with patient-reported health status in a primary care cohort of individuals with chronic obstructive pulmonary disease (COPD), with only MFAP4 demonstrating a modest link to poorer physical quality of life. Chronic obstructive pulmonary disease represents a heterogeneous clinical condition defined by substantial morbid…
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