Scientists Invent ‘Molecular Shield’ for Nose to Treat Hay Fever
UNITED STATES, JUL 9 – The National Allergy Bureau reports pollen counts at decades-high levels this spring, affecting even nonallergic individuals and causing widespread allergy symptoms.
- Researchers in Kazakhstan engineered an antibody from mice that blocks allergic reactions to mugwort pollen when applied inside the nose.
- This development responds to rising hay fever cases linked to factors such as hygiene, antibiotics, lifestyle, diet, pollution, and climate change.
- Mice that had been sensitized to allergens and treated with the XA19 antibody experienced a significant decrease in allergy symptoms, such as reduced ear swelling and less nasal irritation.
- Professor Kaissar Tabynov explained that their approach works quickly and directly within the nasal passages to deactivate the allergen upon exposure, with clinical testing potentially starting within two to three years.
- If successful, this approach could lead to fast-acting, needle-free allergy treatments tailored to individual sensitivities, with market availability in five to seven years.
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Scientists invent ‘molecular shield’ for nose to treat hay fever
A new study offers fresh hope for hay fever sufferers.
Hay fever could soon be treated with a ‘molecular shield’ in the nose
Credit: raquel arocena torres / Moment / Getty Images Plus. Researchers have performed a proof-of-concept study in mice which shows that a ‘molecular shield’ effectively blocks hay fever allergies. The team has engineered an antibody that specifically fights against mugwort pollen, one of the main causes of hay fever allergies. Mugwort pollen is widespread across Europe and Asia, and is endemic in Australia and the Northern Hemisphere. In Austra…
Ask the doctors: Pollen counts are highest they’ve been in decades
Dear Doctors: I have hay fever, but usually it’s not that bad. This year, however, it has been awful. I’m plugged up, my eyes are itchy and by the end of the day, I have a headache. We live near Atlanta, and a lot of people here are miserable. Over-the-counter meds aren’t helping. What can I do? Dear Reader: We suspect your body is responding to pollen, the powdery substance emitted by many plants, grasses and trees in the
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