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Arizona Cardinals rule out quarterback Kyler Murray for rest of season

  • On Dec. 5, 2025, Arizona Cardinals head coach Jonathan Gannon announced that Kyler Murray will not play again this season, saying, 'It wasn't progressing in a way that we wanted,' after further tests and a second opinion.
  • After sustaining the mid-foot sprain in Week 5, Kyler Murray was placed on injured reserve on Nov. 5 following further testing and an out-of-state medical opinion.
  • Statistically, through his five starts Kyler Murray completed 68.3% of his throws for 962 yards, six scores and three interceptions, while veteran backup Jacoby Brissett has averaged more than 300 yards.
  • Jacoby Brissett will keep the starting role as the Arizona Cardinals host the Los Angeles Rams on Sunday in Glendale, Ariz.
  • Financially, the decision leaves the Arizona Cardinals with a $57.7 million dead-cap cost if cut, spread into 2027 with a post-June 1 designation; a trade would save $35.3 million and Kyler Murray has two years remaining on his contract.
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Cardinals QB Kyler Murray ruled out for the rest of the season because of foot injury

Arizona Cardinals quarterback Kyler Murray will miss the remainder of the season because of a foot injury that’s kept him out of the lineup since Week 6.

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profootballrumors.com broke the news in on Friday, December 5, 2025.
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