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AlphaFold2 Model Fails to Link Fibrocystin Variants to ARPKD Severity
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AlphaFold2 Model Fails to Link Fibrocystin Variants to ARPKD Severity
Researchers at the University of Wolverhampton have reported that computational models of the fibrocystin protein generated by AlphaFold2 do not correlate the spatial arrangement of genetic variants with disease severity in Autosomal Recessive Polycystic Kidney Disease (ARPKD).
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