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Nearly half of depression patients struggle with treatment resistance

  • Nearly half of patients diagnosed with depression do not respond to standard treatment, indicating a significant gap in mental healthcare effectiveness.
  • Patients with treatment-resistant depression face worse physical health and shorter lifespans compared to those who respond to treatments.
  • The study found that 36.9% of patients tried four or more different antidepressants without adequate response, leading to feelings of frustration and hopelessness.
  • Researchers emphasize the need for personalized and innovative approaches in treating treatment-resistant depression cases, rather than a 'one-size-fits-all' model.
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Knowridge Science Report broke the news in on Friday, March 21, 2025.
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