Thermostable Formulation Could Free mRNA Vaccines From the Cold Chain
The method produced solid formulations that stayed active for more than 2 months at 37 C and could enable patch-based delivery.
6 Articles
6 Articles
An artificial intelligence algorithm helped MIT researchers adjust lipid nanoparticles to allow experimental formulations of RNA vaccines to withstand more heat. In mouse testing, the formulation maintained immune responses after storing up to one year at room temperature or two months at 37 °C.
A model of MIT AI achieves thermostable mRNA vaccines that retain 100% of their activity two months at 37 °C without cold chain. La entrada An AI accelerates the design of thermostable mRNA vaccines without cold chain aparece primero en Merca2.
American researchers have modified mRNA vaccines so that they can be stored at 37 degrees Celsius for two months and still be fully effective. At room temperature, they remain effective for up to a year. An AI algorithm found the right recipe in one month. An mRNA vaccine does not contain a piece of virus. It contains a building instruction. That instruction, the mRNA, tells […] More science? Read the latest articles on Scientias.nl.
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