Christina Applegate reveals she was misdiagnosed with MS
Doctors say new testing showed Applegate never had multiple sclerosis, but she still has debilitating symptoms and will undergo further investigation.
- On Tuesday, actress Christina Applegate revealed on her podcast MeSsy that she was misdiagnosed with multiple sclerosis in 2021. The 54-year-old tearfully shared that new medical technology led to this discovery after years of believing she had the autoimmune disease.
- Applegate, who first announced her diagnosis in 2021, had become a public advocate for the condition alongside her co-host, The Sopranos actor Jamie-Lynn Sigler. Sigler was diagnosed with multiple sclerosis roughly 25 years ago.
- Returning to the podcast after seven months away, Applegate expressed frustration that she still experiences debilitating symptoms. "This may come as great news, but to me, I'm back at square one," she said, describing the lack of clarity as "unnerving."
- Her medical team is now working to determine the underlying cause of her condition. Although she does not have multiple sclerosis, Applegate continues to rely on a wheelchair, with many illnesses capable of mirroring her symptoms.
- Best known for roles in Married with Children and Dead to Me, the Emmy-nominated actor retired from acting in 2022 due to her health. She previously overcame a breast cancer diagnosis in 2008 and received a standing ovation at the 2024 Emmy Awards.
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Anthony Anderson and Christina Applegate at Emmy 2023 Kevin Winter/Getty Images/AFP Christina Applegate revealed on Tuesday (20), in an episode of her podcast "MeSsy", which did not have multiple sclerosis. The actress received the diagnosis of the disease in 2021. Emotionally, she told the listeners what she heard from the doctor. She entered my room and said: ‘Congratulations, you don't have multiple sclerosis,' remembered Applegate among tear…
In 2021 "A terribly nice family" star Christina Applegate is diagnosed with multiple sclerosis. Apparently a misdiagnosis, as the actress now learns. But she does not feel any joy about it.
Christina Applegate Reveals She Was Misdiagnosed with MS: ‘Why Did This Happen?’
Christina Applegate dropped some major news on her “MeSsy” podcast this week. After months away, she returned to the show to tell listeners she was misdiagnosed with multiple sclerosis. Applegate has suffered from debilitating symptoms and was diagnosed with the disease in 2021. While talking with her co-host Jamie Lynn Sigler, over the course of two episodes that dropped the same day, Christina recalled her doctor giving her the health update. …
Christina Applegate Says She Was Misdiagnosed With MS: 'Back at Square One'
"I had a reason as to why my day sucked every day, and now I don’t have a reason and it’s very unnerving and very confusing," the actress tells "MeSsy" podcast co-host Jamie-Lynn Sigler
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