A US study of more than 3.3 million people linked the EGFR T790M gene variant to lung cancer risk, with no link to 17 other cancers.
4 Articles
4 Articles
Rare Gene Mutation Raises Lung Cancer Risk 60-Fold in Non-Smokers
Researchers have identified a rare genetic mutation that significantly increases the risk of lung cancer, even in individuals who have never smoked. An analysis of data from 3.3 million people revealed a specific malfunction in a gene responsible for cell division. For smokers, this mutation is associated with approximately a 10-fold increase in disease risk. However, the impact is more pronounced in non-smokers: individuals with the mutation wh…
Photo:Shutterstock New research from Dana-Farber and 23andMe has shown that a rare inherited mutation called EGFR T790M strongly increases the risk of lung cancer, especially in people who have never smoked. The findings, published in the journal Science, are based on anonymized, aggregated genetic data from more than 3.3 million 23andMe study participants who consented to use the data, […]
Not smoking doesn't mean you're completely free from lung cancer risk. A new study of more than 3.3 million people found that the rare genetic variant EGFR T790M is associated with approximately a 25 times higher risk of lung cancer in those carrying the variant.
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