A universal 'instruction manual' helps immune cells protect our organs
The transcription factor MafB regulates macrophage maturation and function, with its absence causing organ defects, a process conserved across vertebrates, researchers report.
2 Articles
2 Articles
A universal 'instruction manual' helps immune cells protect our organs
Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs. The MafB factor, a veritable "molecular switch," activates or deactivates certain genes at the right time and in the right place, leading to the production of macrophages responsible for defending our body and supporting the functioning of our organs. Without MafB, macrophages can b…
This Genetic Switch Helps Immune Cells Protect Your Organs
A single genetic “switch” may be the secret to how the body’s cleanup crew grows up and keeps our organs running smoothly. Scientists at the University of Liège have identified a crucial genetic regulator that allows macrophages to fully mature and help maintain healthy organs. This regulator, known as MafB, acts as a “molecular switch” [...]
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