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Having a sense of purpose may protect against dementia: Study

Researchers followed over 13,000 adults for up to 15 years and found higher life purpose linked to a 28% lower risk of cognitive impairment across diverse groups.

  • A recent UC Davis study, published on August 25, 2025, tracked more than 13,000 individuals aged 45 and above over a period of up to 15 years to investigate their risk of developing dementia.
  • Researchers found that individuals with a stronger sense of purpose in life had approximately 28% lower chances of experiencing declines in thinking abilities, such as mild cognitive decline or dementia.
  • The protective effect of purpose remained significant across racial and ethnic groups and after controlling for education, depression, and the APOE4 gene, a known Alzheimer's risk factor.
  • Lead author Nicholas C. Howard noted medications like lecanemab can modestly delay symptoms but come with risks and costs, while purpose in life is free, safe, and accessible through relationships and goals.
  • The results indicate that maintaining positive mental health is important for aging well, and further research should investigate whether fostering a sense of purpose can contribute to dementia prevention.
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A Sense of Purpose Can Protect Aging Brain

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A Sense Of Purpose Can Protect Brain Health In Aging

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Medical Xpress broke the news in on Monday, August 25, 2025.
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