Molecular mechanism that initiates colon cancer opens new path for prevention

Molecular mechanism that initiates colon cancer opens new path for prevention

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental factors and lifestyle, such as poor diet, sedentarism, obesity, smoking or excessive alcohol consumption. Most colorectal cancers arise from adenomatous polyps, a precancerous lesion that may progress to a malignant tumor unless it is detected and removed in time.

Breakthrough Identification of the Molecular Trigger Behind Colon Cancer

A groundbreaking study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has unveiled a previously unrecognized molecular mechanism that instigates colorectal cancer, providing vital new insights into its early onset and progression. This discovery centers on the degradation of the tumor suppressor protein p53, a protein conventionally revered as the “guardian of the genome” for its pivotal role in controlling cell d…

Colon cancer is the most commonly diagnosed cancer in the general Spanish population, according to data from the Spanish Association Against Cancer. According to available evidence, up to 80% of cases are related to various factors […]