New drug technique targets gut inflammation with precision

Oxford researchers develop drug delivery system to tackle antibiotic resistance

A new drug delivery system developed by researchers at Oxford University could help to solve the problem of antibiotic-resistant infections.

New drug technique targets gut inflammation with precision

A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.

A digestive 'treasure chest' shows promise for targeted drug treatment in the gut

A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study, published in Science, introduces a mechanism called "GlycoCaging" that releases medicine exclusively to the lower gut at doses up to 10 times lower than current therapies.

Broken the cell lock to introduce drugs

Was broken the cell lock: thanks to a New drug design methodnow it is possible introduce even quantities considered so far too greati, opening new perspectives for a whole series of Promising treatmentsstarting from those anti-cancerbut they were set aside due to their size. The important result, published in the Cell magazine, is due to the research group of the US Duke University, the University of Texas in San Antonio and the University of Ar…

New method can treat gut disease with fewer side effects

Researchers at the University of British Columbia (UBC) have created a new method to deliver drugs directly to the gut, offering hope for better treatments for inflammatory bowel disease (IBD). This new technique, called GlycoCaging, allows powerful medicines to reach the inflamed part of the gut using much lower doses than current treatments, helping to […] The post New method can treat gut disease with fewer side effects appeared first on Know…

Targeting GI Drug Delivery with GlycoCaging Could Improve IBD Treatments

Scientists headed by a team at the University of British Columbia (UBC) have developed a new approach to drug design that can deliver therapeutics directly to a specific part of the gastrointestinal (GI) tract. The drug delivery system, GlycoCaging, is based on bespoke glycoconjugates of a complex plant oligosaccharide. A proof-of-concept study in mice showed that the system could release drugs exclusively to the lower gut at doses up to 10 time…