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49ers vs. Commanders Best Bets: NFL Odds, Predictions, Expert Picks, Sportsbook Promos and More for MNF

Brock Purdy leads San Francisco’s offense as the 49ers seek a sixth straight win and Washington tries to rebound after a tie and injury setbacks.

Summary by Sporting News
The unbeaten 49ers host the 1-3-1 Commanders on Monday Night Football as 7.5-point favorites.
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8 Articles

Sports IllustratedSports Illustrated
Lean Left

Washington Can Jump From Last to Second in the NFC East Tonight — Commanders Daily

Washington can move from fourth to second in the NFC East with a win over the 5-0 49ers Monday night. A loss would extend the division’s winless streak.

·New York, United States
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New York PostNew York Post
Lean Right

Commanders vs. 49ers prediction, best bet: George Kittle will find the endzone on ‘Monday Night Football’

Read our NFL 'Monday Night Football' betting preview, including odds and best bets for Commanders vs. 49ers

·New York, United States
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Syracuse NYSyracuse NY
Center

Experts update Commanders vs. 49ers MNF prediction as Daniels, Purdy top Underdog Pick’em props

Commanders vs. 49ers predictions for Monday Night Football, featuring expert data projections, the best bet and Underdog Pick’em quarterback props.

·New York, United States
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Sporting NewsSporting News
Center

49ers vs. Commanders best bets: NFL odds, predictions, expert picks, sportsbook promos and more for MNF

The unbeaten 49ers host the 1-3-1 Commanders on Monday Night Football as 7.5-point favorites.

·Charlotte, United States
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NBC SportsNBC Sports
Center

49ers vs Commanders Odds, expert picks, team and player news, betting trends, and stats

San Francisco 49ers vs Washington Commanders Game Preview

·Stamford, United States
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The Courier-JournalThe Courier-Journal
Lean Left

Washington Commanders at San Francisco 49ers odds, picks and predictions

The Washington Commanders and San Francisco 49ers square off on Monday Night Football at Levi's Stadium in Santa Clara, California. Kickoff is 8:15 p.m. ET.

·Louisville, United States
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AZCentral broke the news in Phoenix, United States on Sunday, October 18, 2026.
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