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Aging Muscles May Be Losing Strength for a Reason Scientists Missed

Researchers found aging muscles lose reliable nerve signaling and said blocking the ClC-1 channel improved strength in animal models.

Summary by Science Daily
A newly identified breakdown in communication between nerves and muscles could help explain why people lose strength as they age. Researchers were able to improve muscle strength in an animal model by targeting a key protein, raising hopes that some age-related weakness could eventually be treated.

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Sawalev's muscle weakness with age may not be merely the result of the loss of muscle mass, as widely believed, as researchers have revealed another disorder at the point of contact between nerves and muscles, and may explain an important aspect of the decline in power among older persons. According to Medical Express.

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Researchers at the University of Missouri have identified a hidden cause for age-related muscle weakness, which can pave the way for new treatment strategies. The discovery reveals that communication between nerves...

In a test on mice, the compound protected a signal important for muscle regeneration. It has not yet been proven to prevent muscle loss.

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nin.rs broke the news on Wednesday, September 23, 2026.
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