What You Should Know About ALS, Also Known as Lou Gehrig’s Disease
- Amyotrophic lateral sclerosis , also known as Lou Gehrig's Disease, is a progressive neurodegenerative disorder that affects motor neurons in the brain and spinal cord.
- ALS causes degeneration and death of motor neurons, preventing the brain from transmitting signals to muscles, which leads to muscle weakness, paralysis, and respiratory failure.
- About 5,000 new ALS cases occur annually in the United States, mostly between ages 40 and 70, with sporadic ALS comprising 90% of cases and familial ALS accounting for 5% to 10%.
- Veterans and firefighters face nearly double the risk of developing ALS, possibly linked to occupational exposures, while genetic factors are also significant, with research identifying close to 50 related genes.
- Though no cure exists, therapies approved by the FDA can slow progression, and ongoing clinical trials, research investments, and multidisciplinary care improve outcomes and provide hope for future management.
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What You Should Know About ALS, Also Known as Lou Gehrig’s Disease
SATURDAY, May 3, 2025 (HealthDay News) — Amyotrophic lateral sclerosis (ALS) – known as Lou Gehrig’s Disease based on the iconic 1930s New York Yankee baseball player – is a progressive neurodegenerative disease that affects thousands of Americans every year.…
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