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What is a pulmonary embolism, the condition that led to Catherine O’Hara’s death?

Catherine O’Hara died suddenly from a pulmonary embolism, a blood clot in the lungs linked to her underlying rectal cancer, a leading cause of death in cancer patients, experts said.

  • On Jan. 30, Catherine O'Hara died at her Los Angeles home after a brief illness, with the County of Los Angeles listing a pulmonary embolism as the cause.
  • A pulmonary embolism occurs when a blood clot formed elsewhere lodges in pulmonary arteries, blocking blood flow and oxygen delivery; people over 60 and those with cancer face higher risk, and rectal cancer was listed on O'Hara's death certificate.
  • Emergency responders were called after she had breathing difficulty around 4:48 a.m., and the Los Angeles Fire Department transported O'Hara to hospital in 'serious' condition.
  • Medical guidance stresses PE is an emergency needing prompt treatment, typically starting with anticoagulation, while severe cases may require thrombolytic medications or clot-removal procedures.
  • Countless colleagues paid tribute, including Eugene Levy and Seth Rogen, with Levy praising his more than 50-year friendship and collaboration with Catherine O'Hara.
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What is a pulmonary embolism, the condition that led to Catherine O’Hara’s death?

Catherine O’Hara’s death from a pulmonary embolism has drawn attention to this serious condition in which a blood clot lodges in the lungs. Dr. Leana Wen explains.

·Atlanta, United States
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TMZ broke the news in Los Angeles, United States on Wednesday, February 18, 2026.
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