Two New Compounds Could Unlock Hidden Drivers of Alzheimer's Disease

Two New Compounds Could Unlock Hidden Drivers of Alzheimer's Disease

Vanderbilt University researchers have created two novel chemical tools that could expose overlooked mechanisms behind Alzheimer’s disease. One compound selectively shuts down a little-understood protein called TAOK1, while a second unexpectedly activates the entire TAOK protein family. Together, they give scientists a new way to probe what these proteins actually do in the brain and how they might contribute to dementia. This article explains w…

Learning Alzheimer’s disease signatures by bridging EEG with spiking neural networks and biophysical simulations