New Antibody Therapy Promotes Nerve Regeneration After Spinal Cord Injury

New antibody therapy promotes nerve regeneration after spinal cord injury

An international research group recently demonstrated that the antibody NG101 promotes the regeneration of damaged spinal cord tissue.

Anti-Nogo-A Treatment Alters Spinal Cord Structure Post-Injury

In a groundbreaking study published in Nature Communications, researchers have unveiled remarkable insights into the therapeutic potential of Anti-Nogo-A NG101 treatment in spinal cord injury (SCI). This novel intervention targets the fundamentally challenging problem of neural regeneration, offering hope for unprecedented recovery avenues in patients suffering from the debilitating consequences of spinal trauma. The significance of this advance…

Antibody Promotes Nerve Regeneration in Spinal Cord Injury Patients

Swiss research shows treatment with an antibody known as NG101 promotes regeneration of damaged spinal cord tissue in some people with spinal cord injury by blocking a protein called Nogo-A that normally suppresses nerve regrowth in the central nervous system. Compared to placebo, participants treated with the antibody showed faster lesion volume shrinkage and a significantly slower loss of spinal cord tissue, both in terms of size and myelin co…

The Protein That Blocks Nerve Repair After Spinal Cord Injury Has Been Stopped

Nogo-A has been getting in the way for thirty years. The protein sits in the sheaths of nerve fibers throughout the spinal cord and brain, doing nothing obviously useful, yet doing something extremely effective: stopping damaged nerves from healing. After injury, when the body desperately needs axons to regrow and reconnect, Nogo-A is still there, blocking the process like a bouncer who doesn’t know the party’s over. Researchers at the Universit…