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Tec-Dara Could Represent a New Standard of Care for Relapsed or Refractory Multiple Myeloma

Teclistamab plus daratumumab reduced risk of disease progression or death by 83% and improved 36-month overall survival to 83.3%, researchers reported.

Summary by Medical Xpress
Patients with relapsed or refractory (R/R) multiple myeloma who received a combination of teclistamab, a bispecific monoclonal antibody, and daratumumab, a CD38-directed monoclonal antibody, were 83% more likely to be alive without disease progression compared with those who received standard second-line therapies at a median of nearly 35 months of follow-up, according to the results of a new trial presented at the 67th American Society of Hemat…

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Phase 2 data support further evaluation of frontline BCMA/CD3 bispecific antibody combinations in phase 3 trials.

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PR Newswire broke the news in United States on Tuesday, December 9, 2025.
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