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Tamiflu isn’t the only flu treatment available. These other options may fly under the radar – and provide relief

The CDC recommends four antiviral drugs for flu treatment with benefits varying by age, dosing, side effects, and cost, emphasizing early use within two days of symptoms.

  • The US Centers for Disease Control and Prevention recommends four antiviral drugs—Tamiflu and Xofluza —available in multiple formulations to treat or prevent influenza in the United States.
  • Tamiflu treats patients as young as two weeks with twice daily doses for five days, while Xofluza offers a single-dose oral treatment for those 5 years and older.
  • Clinicians note a 2023 study found 18% vomiting with Tamiflu versus 5% with Xofluza, while Tamiflu costs about $50 and Xofluza nearly $200 without insurance.
  • Antivirals work best when started within two days of symptom onset, so pharmacy stock and clinician preferences lead to Tamiflu being recommended more often despite its five-day course.
  • Resistance data indicate experts warn of growing concern about resistance to Xofluza , with CDC officials noting it appears more often in younger children and links to longer symptoms, but limited spread.
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Tamiflu isn’t the only recommended flu treatment in the US. These are the others.

When the flu strikes, it can feel relentless: rising fever, hacking cough, stuffy nose and sore throat. For many people, relief can come in the form of Tamiflu, a prescription antiviral medication used to treat and even prevent the illness.

·Atlanta, United States
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WAAY-TV broke the news in Huntsville, United States on Friday, December 26, 2025.
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