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Study Finds Exploiting ‘Fruitless’ Gene Could Stop Mating Mosquitoes
Mutating the gene cut male yellow fever mosquitoes' hearing to one-sixth of normal and blocked attraction to female wingbeats, researchers said.
In a new study published in PLOS Biology, researchers identified the 'fruitless' gene as the mechanism allowing male Aedes mosquitoes to locate females by listening for wingbeat sounds.
Scientists have long studied reproductive mechanisms to control disease-spreading mosquitoes, including Zika, by understanding how males detect females via wingbeat frequencies—450 Hz for females versus 750 Hz for males.
Collaborating with Daniel Eberl from the University of Iowa, Nagoya University researchers found that mutating the 'fruitless' gene impairs auditory neuron response, causing mutant males to exhibit female-like behavior.
"This research revealed that fruitless is responsible for establishing male auditory function," Eberl said, adding that targeting this gene and its downstream molecular motor proteins could interfere with mosquito reproduction.
This breakthrough provides a new strategy for population control, as males rely on Johnston organ auditory neurons to modulate hearing and locate partners, potentially decimating disease-spreading populations by preventing mating.
(Seoul = Yonhap News) Reporter Lee Joo-young = A gene involved in male mosquitoes locating females by listening to the sound of their wings to mate has been identified. This gene contains...