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Why Ozempic Doesn’t Work for Everyone: Scientists Just Found a Hidden Reason

The findings suggest about 10% of people carry variants that blunt blood sugar control on GLP-1 treatment, researchers said.

Summary by Science Daily
A new study reveals that popular diabetes and weight-loss drugs like Ozempic and Wegovy may not work as effectively for about 10% of people due to specific genetic variants. These individuals appear to have a puzzling condition called “GLP-1 resistance,” where their bodies produce higher levels of the hormone targeted by these drugs—but don’t respond to it properly.

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Researchers have been able to identify specific genetic mutations that help predict the degree of weight loss and potential for side effects, which may explain why some lose more weight than others while others are more affected by complications. These findings, published in the Nature Patrol, open the door to what is known as micromedicine, where doctors can in future devote weight reduction treatment according to the genetic profile of each pa…

·Iraq
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Many patients with type 2 diabetes take agonists from the GLP-1 receptor, a class of medicines such as Ozempic and Mounjaro. But these medications may not work so well for people with certain genetic variants, according to a new study by researchers at Stanford Medicine. Panic Environment: 'It is a myth that always exists a cause', explains the fossil fossil found in South Africa is the oldest evidence that ancestors of mammals bottled eggs The …

·Brazil
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GLP-1 drugs like Ozempic don't work on all of them. Researchers have now discovered two genes that could explain why – with surprising consequences.

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NDTV broke the news in New Delhi, India on Saturday, April 11, 2026.
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