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Simcere Zaiming Announces First Patient Dosed in the US in a Phase 1 Trial of ...

  • Simcere Zaiming announced that the first US patient has begun treatment in a Phase 1 trial at The Tisch Cancer Institute, assessing the safety and preliminary efficacy of SIM0500 in relapsed/refractory multiple myeloma patients.
  • SIM0500 is a humanized trispecific antibody targeting GPRC5D, BCMA, and CD3, developed with Simcere Zaiming's proprietary platform.
  • In April 2024, the FDA granted SIM0500 a Fast Track designation due to its potential in treating RRMM, emphasizing its promise as a cornerstone for future therapies.
  • BCMA and GPRC5D-targeted therapies have shown significant promise in treating RRMM and are expected to play a key role in future treatments.
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Fox 4 Kansas CityFox 4 Kansas City
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Simcere Zaiming Announces First Patient Dosed in the US in a Phase 1 Trial of Trispecific Antibody SIM0500 in Patients with Relapsed/Refractory Multiple Myeloma

·Kansas City, United States
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Fox 4 Kansas City broke the news in Kansas City, United States on Wednesday, June 18, 2025.
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